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Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
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The troubled puberty of malaria parasites
Jonas Gockel1, Till S Voss2, Richárd Bártfai1
1Department of Molecular Biology, Radboud University, 6525GA Nijmegen, The Netherlands.
Trends in Parasitology
|January 26, 2023
Abstract:
Sexual differentiation of malaria parasites is essential for transmission, yet the underlying mechanisms are poorly understood. Russell et al. elegantly combined a loss-of-function screen with single-cell RNA-sequencing to identify key factors in this process. Gomes et al. further characterized one of them, MD1, as a regulator contributing to male fate determination.
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