Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

Chronic Pharyngitis

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pulmonary lymphangiomatosis: insights into an ultra-rare disease.

Respiratory research·2024

Same author

Cocaine use in trauma: the vices-paradox revisited.

Surgery·2023

Same author

[Smoking-toxic substances and immunological consequences].

Radiologie (Heidelberg, Germany)·2022

Same author

Position statement on endoscopic lung volume reduction in South Africa: 2022 update.

African journal of thoracic and critical care medicine·2022

Same author

Canadian Surgery Forum 2018: St. John's, NL Sept. 13-15, 2018.

Canadian journal of surgery. Journal canadien de chirurgie·2022

Same author

Analysis of Neutral B-Meson Decays into Two Muons.

Physical review letters·2022

Same journal

Innere Medizin (Heidelberg, Germany)·2026

Same journal

Innere Medizin (Heidelberg, Germany)·2026

Same journal

Innere Medizin (Heidelberg, Germany)·2026

Same journal

[Optimal blood pressure control in patients with diabetes and arterial hypertension: interpreting the BPROAD study].

Innere Medizin (Heidelberg, Germany)·2026

Same journal

[Distributive justice in healthcare during times of change: a medical ethics perspective].

Innere Medizin (Heidelberg, Germany)·2026

Same journal

[Update on the pharmacotherapy of chronic heart failure with reduced ejection fraction: from four to six pillars?]

Innere Medizin (Heidelberg, Germany)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Aug 12, 2025

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

[Chronic cough].

M Schellenberg¹, F J F Herth²

¹Pneumologie und Beatmungsmedizin, Thoraxklinik am Universitätsklinikum Heidelberg, Translational Lung Research Center Heidelberg (TLRC), Universität Heidelberg, Röntgenstr. 1, 69126, Heidelberg, Deutschland. mavi.schellenberg@med.uni-heidelberg.de.

Innere Medizin (Heidelberg, Germany)

|January 26, 2023

Summary

This summary is machine-generated.

Coughing is a vital reflex for clearing airways, but a chronic cough lasting over 8 weeks requires careful diagnosis. This review outlines diagnostic steps and treatments for persistent cough to ensure accurate care.

Keywords:

Antitussive agents Chronic idiopathic cough Cough/diagnosis, differential Cough/etiology Interdisciplinary diagnostic process

More Related Videos

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

Published on: September 27, 2024

Related Experiment Videos

Last Updated: Aug 12, 2025

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Establishment of a Mouse Model with Cough Hypersensitivity via Inhalation of Citric Acid

Published on: January 10, 2025

Methods for Detecting Cough and Airway Inflammation in Mice

Methods for Detecting Cough and Airway Inflammation in Mice

Published on: August 2, 2024

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

Author Spotlight: Evaluating the Therapeutic Efficacy of Moving Cupping Along Meridians for Acute Exacerbation of COPD

Published on: September 27, 2024

Area of Science:

Respiratory Medicine
Pulmonology
Clinical Diagnostics

Context:

Coughing is a common respiratory reflex essential for bronchial clearance.
Persistent cough exceeding 8 weeks is defined as chronic cough.
Chronic cough presents a diagnostic challenge in outpatient settings, often indicating diverse underlying conditions.

Purpose:

To outline current diagnostic procedures for chronic cough.
To discuss essential differential diagnoses for persistent cough.
To present evidence-based treatment options for chronic cough.

Summary:

This article reviews the diagnostic approach to chronic cough, emphasizing a structured, interdisciplinary process.
It covers key differential diagnoses, aiming to identify causal factors for effective treatment.
The focus is on avoiding both overdiagnosis and the omission of severe pathologies.

Impact:

Facilitates accurate diagnosis and management of chronic cough.
Provides clinicians with a framework for evaluating persistent cough symptoms.
Aims to improve patient outcomes by guiding appropriate therapeutic interventions.