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Updated: Aug 12, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
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Dual sequence definition increases the data storage capacity of sequence-defined macromolecules

Katharina S Wetzel1, Maximiliane Frölich1, Susanne C Solleder1

  • 1Laboratory of Applied Chemistry, Institute of Organic Chemistry (IOC), Karlsruhe Institute of Technology (KIT), Straße am Forum 7, 76131, Karlsruhe, Germany.

Communications Chemistry
|January 27, 2023
PubMed
Summary

Researchers developed dual sequence-defined oligomers for enhanced data storage. This molecular approach significantly increases data storage capacity per molecule, overcoming previous limitations in sequence precision and purity.

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