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Updated: Aug 6, 2026

A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb (BCG lux/M.Tb lux)
Published on: September 14, 2011
A recovered case of generalized BCG infection
Abstract:
A female infant was at the age of 8 months admitted with muco-cutaneous candidiasis. The applied therapy was inefficacious. Subsequent examinations pointed to a combined humoral and cellular immunopathy. At the age of 7 years the patient was readmitted with abdominal complaints. Diagnostic laparotomy revealed a tuberculous mesenterial growth. The isolated agent proved to be a BCG strain. Antituberculous therapy was beneficial, the tumour dissappeared and full recovery was attained. The mycotic process remained unchanged and still needs continuous treatment.
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