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Related Experiment Videos

Transcranial Doppler in brain death.

A H Ropper1, S M Kehne, L Wechsler

  • 1Neurology-Neurosurgery Intensive Care Unit, Massachusetts General Hospital, Boston 02114.

Neurology
|November 1, 1987
PubMed
Summary
This summary is machine-generated.

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Transcranial Doppler (TCD) studies in brain-dead patients revealed persistent blood flow in middle cerebral arteries in most cases. A specific Doppler pattern may aid in diagnosing brain death, while normal patterns likely exclude it.

Area of Science:

  • Neurology
  • Neuroscience
  • Medical Imaging

Background:

  • Diagnosing brain death requires confirmation of absent brainstem reflexes and cessation of cerebral blood flow.
  • Transcranial Doppler (TCD) is a non-invasive ultrasound technique used to assess cerebral blood flow velocity.

Purpose of the Study:

  • To investigate the utility of Transcranial Doppler (TCD) in diagnosing brain death by characterizing cerebral blood flow patterns.

Main Methods:

  • Performed Transcranial Doppler (TCD) examinations on 24 adult patients diagnosed with brain death.
  • Analyzed Doppler shift frequencies and flow patterns within the middle cerebral arteries.

Main Results:

  • Persistent blood flow in the middle cerebral arteries was observed in 21 out of 24 brain-dead patients.

Related Experiment Videos

  • A characteristic Doppler pattern (anterograde systolic envelope with reversed diastolic flow) was identified in 14 patients.
  • Three patients with absent brainstem reflexes but persistent EEG activity showed normal TCD patterns.

    • Conclusions:

    • The characteristic TCD pattern may serve as a valuable ancillary tool in the diagnosis of brain death.
    • Normal TCD findings likely exclude the diagnosis of brain death, suggesting preserved cerebral circulation.