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Related Experiment Video

Updated: Aug 12, 2025

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Three-dimensional soft tissue landmark detection with marching cube algorithm.

Yoonjung Lee1, Ji-Min Lee1,2, Sun-Hyung Park1,2

  • 1Department of Orthodontics, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Scientific Reports
|January 28, 2023
PubMed
Summary
This summary is machine-generated.

A new method for analyzing 3D soft tissue data significantly improves reliability compared to existing software. This technique, using the marching cube algorithm and a computer-calculated point, reduces human error in landmark digitization.

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Area of Science:

  • Medical Imaging
  • Orthodontics
  • Biometrics

Background:

  • Current 3D soft tissue analysis, particularly frontal view, suffers from subjectivity and low reliability.
  • This impacts the accuracy of diagnostic and treatment planning in fields like orthodontics.

Purpose of the Study:

  • Introduce and evaluate a novel method for analyzing 3D soft tissue data using the marching cube algorithm (Program S).
  • Compare the reliability of Program S against a commercial software (Program A).
  • Assess the efficacy of a developed computer-calculated point (CC point) in reducing human error.

Main Methods:

  • Utilized cone-beam computed tomography (CBCT) images from 42 patients.
  • Two orthodontists digitized six facial landmarks twice using both Program S and Program A at two-week intervals.
  • Calculated intra- and inter-examiner reliability and compared coordinate values and distances between programs.

Main Results:

  • Program S demonstrated significantly higher intra- and inter-examiner reliability (99.7-100% and 99.9-100%) compared to Program A (64.0-99.9% and 76.1-99.9%).
  • Program S showed reduced inter-examiner differences in coordinate values and distances for all landmarks.
  • The developed CC point provided a consistent, single landmark for analysis.

Conclusions:

  • The new methodology using the marching cube algorithm (Program S) enhances intra- and inter-examiner reliability in 3D soft tissue landmark digitization.
  • The computer-calculated point (CC point) offers a viable solution to minimize human error in soft tissue analysis.