Emerging plasmonic nanoparticles and their assemblies for cancer radiotherapy

Area of Science:

• Nanotechnology
• Biomedical Engineering
• Radiotherapy

Background:

• Plasmonic nanoparticles and assemblies are utilized in biosensing, imaging, and medicine.
• High-Z plasmonic nanomaterials can sensitize radiotherapy due to their properties.
• Assembled structures offer tunable properties for drug delivery and cancer treatment.

Purpose of the Study:

• To review plasmonic nanoparticles and their assemblies for cancer radiotherapy.
• To introduce the sensitization mechanism of plasmonic radiosensitizers.
• To discuss recent progress, challenges, and future perspectives.

Main Methods:

• Review of existing literature on plasmonic nanoparticles in cancer radiotherapy.
• Classification of recent progress based on structure and shape.
• Analysis of sensitization mechanisms and applications.

Main Results:

• Plasmonic nanomaterials effectively sensitize radiotherapy.
• Assembled structures demonstrate versatile applications in drug delivery and cancer treatment.
• Progress is systematically discussed based on structural and shape classifications.

Conclusions:

• Plasmonic nanoparticles and assemblies hold significant potential for advancing cancer radiotherapy.
• Further research is needed to address current challenges and unlock future perspectives.
• Tunable properties of assembled structures are key for enhanced therapeutic outcomes.