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Influenza Vaccine and COVID-19 Pandemic: Could This Vaccine Help Limit the Potential Adverse Consequences of

Reza Mosaed1, Hossein Fasihi2, Amir Norouzi3

  • 1Department of Clinical Pharmacy, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.

Iranian Journal of Pharmaceutical Research : IJPR
|January 30, 2023
PubMed

Insights

The influenza vaccine does not impact COVID-19 mortality. However, it reduces hospitalization costs for individuals over 65 with chronic conditions, offering insights into public health strategies.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Vaccinology

Background:

  • The COVID-19 pandemic necessitated urgent research into treatments and vaccines for SARS-CoV-2.
  • Hypotheses suggested potential benefits of existing respiratory virus vaccines, such as the measles, mumps, and rubella (MMR) vaccine, in mitigating COVID-19 pneumonia severity, morbidity, and mortality.
  • The influenza vaccine is widely utilized and covered by Iranian insurance, presenting an opportunity for comparative study.

Purpose of the Study:

  • To investigate the effect of the influenza vaccine on COVID-19 mortality.
  • To assess the influenza vaccine's impact on hospitalization costs in COVID-19 patients.

Main Methods:

  • A comparative study involving 3,379 participants aged 20-75 years.
  • Analysis focused on individuals who received the influenza vaccine.
  • Comparison of COVID-19 mortality rates and hospitalization costs between vaccinated and unvaccinated groups (implied).

Main Results:

  • The influenza vaccine demonstrated no significant effect on mortality caused by COVID-19 pneumonia.
  • A notable decrease in hospitalization costs was observed in individuals over 65 years with a history of chronic disease who received the influenza vaccine.
  • The study identified a specific subgroup benefiting from influenza vaccination regarding healthcare expenditure.

Conclusions:

  • Influenza vaccination does not appear to influence COVID-19 related mortality.
  • Influenza vaccination may offer economic benefits by reducing hospitalization costs for elderly patients with chronic conditions during the COVID-19 pandemic.
  • Further research could explore the mechanisms behind cost reduction and its implications for healthcare resource allocation.
Keywords:
COVID-19InfluenzaMortalityPneumoniaVaccine

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