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Updated: Aug 12, 2025

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
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A high-performance speech neuroprosthesis.

Francis R Willett, Erin Kunz, Chaofei Fan

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    |January 30, 2023
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    Summary
    This summary is machine-generated.

    This study introduces a new speech brain-computer interface (BCI) that decodes attempted speech from brain signals. This advanced BCI offers faster, more accurate communication for individuals with paralysis, approaching natural conversation speeds.

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    Area of Science:

    • Neuroscience
    • Biomedical Engineering
    • Assistive Technology

    Background:

    • Speech brain-computer interfaces (BCIs) aim to restore communication for individuals with paralysis.
    • Existing speech BCIs lack the accuracy and speed for unconstrained communication from large vocabularies.

    Approach:

    • Developed a novel speech-to-text BCI utilizing high-resolution intracortical microelectrode array recordings of neural activity.
    • The BCI decodes spiking activity associated with attempted speech movements.

    Key Points:

    • Achieved a 9.1% word error rate on a 50-word vocabulary and 23.8% on a 125,000-word vocabulary, significantly outperforming prior speech BCIs.
    • Decoded speech at 62 words per minute, substantially faster than previous BCI records and approaching natural conversation.
    • Identified key neural code features for speech, including spatially intermixed tuning and persistent articulatory representations, even years after paralysis onset.

    Conclusions:

    • This intracortical speech BCI demonstrates a viable method for restoring rapid communication in individuals unable to speak due to conditions like ALS.
    • The findings pave the way for more effective assistive communication technologies.