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Crown Ethers

Crown Ethers

Crown ethers are cyclic polyethers that contain multiple oxygen atoms, usually arranged in a regular pattern. The first crown ether was synthesized by Charles Pederson while working at DuPont in 1967. For this work, Pedersen was co-awarded the 1987 Nobel Prize in Chemistry. Crown ethers are named using the formula x-crown-y, where x is the total number of atoms in the ring and y is the number of ether oxygen atoms. The term 'crown' refers to the crown-like shape that these ether...

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Related Experiment Video

Updated: Aug 12, 2025

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles

Published on: November 14, 2018

Ion sensors with crown ether-functionalized nanodiamonds.

Changhao Li^1,2, Shao-Xiong Lennon Luo³, Daniel M Kim¹

¹Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

|January 30, 2023

Summary

Researchers developed novel nanodiamond sensors for detecting sodium ions. These sensors utilize nitrogen-vacancy centers and crown ethers, enabling selective ion detection for potential medical diagnostics.

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Last Updated: Aug 12, 2025

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Published on: July 22, 2013

Area of Science:

Nanotechnology
Quantum Sensing
Biomedical Diagnostics

Background:

Alkali metal ions like sodium and potassium are crucial in biological systems.
Accurate detection and quantification of these ions are vital for medical diagnostics and bioimaging.
Fluorescent nanoparticles offer nanoscale imaging capabilities but require enhanced specificity.

Approach:

Grafted crown ether structures onto the surface of nanodiamonds (NDs).
Utilized nitrogen-vacancy (NV) centers in diamond for their optical stability and sensing capabilities.
Developed a method to detect specific alkali ions, such as sodium cations, by observing changes in NV center photoluminescence.

Key Points:

Crown ether functionalization on nanodiamonds enables selective alkali ion binding.
Sodium ion detection is achieved through measurable changes in the charge state of NV centers.
Photoluminescence spectroscopy of NV centers serves as the readout mechanism.

Conclusions:

This work presents a novel approach for creating selective biosensors based on NV centers in diamond.
The developed sensors offer a promising platform for sensitive and specific detection of biologically relevant ions.
Potential applications include advanced medical diagnostics and real-time bioimaging of ion dynamics.