Related Experiment Video
Updated: Jun 21, 2026
09:45
Microfluidics-based High-throughput Circulating Tumor Cell Sorting and Single-cell Sequencing Technology
Published on: November 14, 2025
A multimodal single-cell framework for ecosystem-level profiling of circulating tumor and non-tumor cells
Gabriela Felix1,2, Francesca Aguirre3,4, Lisa Zhou3
1Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA. gabriela.felix@moffitt.org.
Experimental Hematology & Oncology
|June 19, 2026
Summary
Multimodal profiling of circulating tumor cells (CTCs) in advanced colorectal cancer patients revealed genomic instability and heterogeneity. This blood-based analysis offers deeper insights into tumor biology than cell counting alone.
Area of Science:
- Oncology
- Genomics
- Cell Biology
Background:
- Circulating tumor cells (CTCs) are crucial biomarkers in advanced colorectal cancer.
- Current analyses often focus on CTC enumeration, potentially missing deeper biological insights.
- Understanding CTC biology and the tumor microenvironment is key for effective cancer management.
