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Release kinetics of potassium aspartate in polyvinyl chloride matrix formulation
S N Gaizer1, K Pintye-Hódi, B Selmeczi
1Department of Pharmaceutical Technology, Szeged, University of Medical Sciences, Hungary.
Die Pharmazie
|July 1, 1987
Abstract:
The authors prepared potassium aspartate matrix tablets in combination with polyvinyl chloride. The physical parameters were measured and the dissolution rates were determined. During the in vitro release rate experiments, it was determined that the dissolution kinetics obey both zero order and Higuchi diffusion model order kinetics.