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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Aug 12, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

495

Visual field progression in open-angle glaucoma after refractive corneal ablation surgery.

Yu Tang1,2, Xiang Fan1,3, Minshu Wang1,3

  • 1Department of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China.

Lasers in Medical Science
|January 30, 2023
PubMed
Summary

Open-angle glaucoma patients with prior refractive corneal ablation surgery showed faster visual field progression. Enhanced anti-glaucoma treatment is recommended for these individuals.

Keywords:
Intraocular pressurePrimary open-angle glaucomaRefractive corneal ablation surgeryRefractive regressionVisual field progression

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Corneal Surgery Outcomes

Background:

  • Open-angle glaucoma (OAG) management requires monitoring visual field (VF) progression.
  • Previous refractive corneal ablation surgery (RCAS) may influence glaucoma progression.
  • Understanding these effects is crucial for patient management.

Purpose of the Study:

  • To investigate and compare visual field progression in OAG patients with and without a history of RCAS.
  • To identify factors associated with VF progression in the RCAS group.
  • To inform clinical practice regarding treatment strategies.

Main Methods:

  • Retrospective study comparing 21 OAG subjects with RCAS (RCAS group) and 36 OAG subjects without RCAS (non-RCAS group).
  • Visual field progression assessed using the non-parametric progression analysis (NPA) method.
  • Intraocular pressure (IOP) reduction and refractive regressions were analyzed.

Main Results:

  • Higher likelihood of VF progression in the RCAS group (57.1%) compared to the non-RCAS group (25.0%) (p=0.01).
  • The RCAS group showed a significantly lower percentage of IOP reduction with medication (p=0.037).
  • Refractive regression was strongly associated with likely VF progression (91.7% in progressed eyes vs. 33.3% in non-progressed eyes).

Conclusions:

  • Visual field progression in OAG is accelerated following RCAS compared to myopic OAG without RCAS.
  • Patients with OAG and a history of RCAS may require more intensive IOP management.
  • Active enhancement of anti-glaucoma treatment is advised for OAG patients with prior RCAS.