Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Design Example: Aggregate Gradation

Design Example: Aggregate Gradation

The right type and quality of aggregates are crucial for concrete as they significantly influence its properties, mix proportions, and cost-effectiveness. If different sources are available for sand, the commonly used fine aggregate in concrete, the selection of sand is primarily based on its gradation.
The grading, or particle-size distribution, of sand is determined using sieve analysis, with standard sizes ranging from 150 μm to 10 mm (ASTM No. 100 sieve to 3⁄8 in. sieve). Sand is...

Oligosaccharide Assembly

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Development and characterization of AXT@metal-organic framework: A biocompatible, pH-responsive nanocarrier for targeted axitinib delivery in MCF-7 cancer cells.

Annales pharmaceutiques francaises·2025

Same author

Formulation, Evaluation, and Characterization of Ibuprofen Nanocrystals Tablets with Conventional Market Product.

International journal of pharmaceutical compounding·2023

Same author

Natural Bridged Bicyclic Peptide Macrobiomolecules from <i>Celosia argentea</i> and <i>Amanita phalloides</i>.

Mini reviews in medicinal chemistry·2022

Same author

Towards the Synthesis of a Heterocyclic Analogue of Natural Cyclooligopeptide with Improved Bio-properties.

Current organic synthesis·2021

Same author

Structural and biological aspects of natural bridged macrobicyclic peptides from marine resources.

Archiv der Pharmazie·2021

Same author

Revealing facts behind spray dried solid dispersion technology used for solubility enhancement.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society·2016

Search research articles

Related Experiment Video

Updated: Aug 12, 2025

Author Spotlight: Innovative Ice Cream Melting Behavior Analysis Through a Computer Vision System

Author Spotlight: Innovative Ice Cream Melting Behavior Analysis Through a Computer Vision System

Published on: October 4, 2024

Design and Development of Agglomerated Isomalt.

Nikita N Chauhan¹, Jayvadan K Patel²

¹Nootan Pharmacy College, Sankalchand Patel University, Visnagar, Gujarat, India. chauhan.nikita.nikita@gmail.com.

International Journal of Pharmaceutical Compounding

|January 31, 2023

Summary

Melt granulation effectively produced agglomerated isomalt using glyceryl monostearate. This process maintained isomalt

More Related Videos

Designing Silk-silk Protein Alloy Materials for Biomedical Applications

Designing Silk-silk Protein Alloy Materials for Biomedical Applications

Published on: August 13, 2014

Fabrication of a Crystalline Nanocellulose Embedded Agarose Biomaterial Ink for Bone Marrow-Derived Mast Cell Culture

Fabrication of a Crystalline Nanocellulose Embedded Agarose Biomaterial Ink for Bone Marrow-Derived Mast Cell Culture

Published on: May 11, 2021

Related Experiment Videos

Last Updated: Aug 12, 2025

Author Spotlight: Innovative Ice Cream Melting Behavior Analysis Through a Computer Vision System

Author Spotlight: Innovative Ice Cream Melting Behavior Analysis Through a Computer Vision System

Published on: October 4, 2024

Designing Silk-silk Protein Alloy Materials for Biomedical Applications

Designing Silk-silk Protein Alloy Materials for Biomedical Applications

Published on: August 13, 2014

Fabrication of a Crystalline Nanocellulose Embedded Agarose Biomaterial Ink for Bone Marrow-Derived Mast Cell Culture

Fabrication of a Crystalline Nanocellulose Embedded Agarose Biomaterial Ink for Bone Marrow-Derived Mast Cell Culture

Published on: May 11, 2021

Area of Science:

Pharmaceutical Technology
Materials Science

Background:

Isomalt is a sugar substitute with potential applications in pharmaceuticals.
Improving the flow properties of isomalt powder is crucial for manufacturing processes.

Purpose of the Study:

To prepare agglomerated isomalt using a melt granulation process.
To evaluate the physicochemical properties of the resulting agglomerated isomalt.

Main Methods:

Melt granulation of isomalt powder with glyceryl monostearate (0.5%) at its melting point.
Characterization using Fourier Transform Infrared Spectroscopy (FTIR), Differential Scanning Calorimetry (DSC), Scanning Electron Microscopy (SEM).
Evaluation of solubility profiles and flow properties compared to pure isomalt and galenIQ 721.

Main Results:

Melt granulation successfully produced agglomerated isomalt granules.
FTIR and DSC confirmed no chemical structure changes in isomalt post-granulation.
Agglomerated isomalt exhibited similar solubility to galenIQ 721 and improved flow properties.
SEM analysis indicated promising agglomerate formation.

Conclusions:

Melt granulation is a viable method for producing agglomerated isomalt with enhanced properties.
The process preserves the chemical integrity of isomalt.
Agglomerated isomalt shows potential for pharmaceutical applications due to improved characteristics.