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Do sleep disturbances contribute to comorbidities in HIV?
1Minneapolis Veterans Affairs Healthcare System.
Current Opinion in HIV and AIDS
|February 1, 2023
Summary
Sleep disorders are more common in people with HIV (PWH), particularly insomnia. Poor sleep in PWH is linked to other health conditions like heart attack, depression, and pain.
Area of Science:
- Sleep Medicine
- Infectious Diseases
- Public Health
Background:
- Sleep disorders are more prevalent in people with HIV (PWH) compared to seronegative individuals.
- Insomnia is particularly common, with prevalence estimates ranging from 21-35% in PWH.
- Sleep apnea prevalence in PWH is variable and may not be higher than in controls.
Approach:
- This review highlights recent publications on sleep disorders and health in adult PWH.
- Focus is placed on the relationship between sleep and comorbidities in PWH.
- Analysis includes recent findings on insomnia, sleep apnea, and their associations with other health issues.
Key Points:
- Recent studies link insomnia in PWH to myocardial infarction, depressive symptoms, and pain.
- Associations between sleep and cognitive function in PWH are inconsistent.
- PWH report poorer sleep health dimensions, with mixed associations with cognition and depression.
Conclusions:
- Sleep disorders and poor sleep health are significant issues for PWH and are associated with comorbidities.
- Further longitudinal studies and clinical trials are necessary to understand these relationships better.
- Clinical trials for insomnia interventions in PWH are particularly warranted.
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