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Updated: Aug 12, 2025

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
A sprayed graphene transistor platform for rapid and low-cost chemical sensing
Benji Fenech-Salerno1, Martin Holicky1, Chengning Yao1
1Imperial College London, Department of Chemistry, Molecular Sciences Research Hub, 82 Wood Lane, London W12 0BZ, UK. f.torrisi@imperial.ac.uk.
We developed a novel Lab-on-PCB platform using sprayable graphene ink for affordable, scalable chemical sensor test strips. This versatile technology accurately detects pH and sodium ion concentrations in solutions.
Area of Science:
- Materials Science
- Chemical Engineering
- Electronics Engineering
Background:
- Graphene field-effect transistors (GFETs) offer high sensitivity for chemical sensing.
- Developing cost-effective and scalable manufacturing methods for GFET-based sensors remains a challenge.
Purpose of the Study:
- To demonstrate a novel, versatile, and scalable sensing platform for chemical sensor test strips.
- To utilize electrolyte-gated GFETs and a Lab-on-PCB approach for sensor fabrication.
Main Methods:
- Fabrication of a Lab-on-PCB platform using sprayable graphene ink.
- Development of electrolyte-gated graphene field-effect transistors.
- Testing the platform's performance for sensing pH and Na+ concentrations in aqueous solutions.
Main Results:
- Achieved high sensitivity for pH sensing (143 ± 4 μA per pH).
- Demonstrated high sensitivity for Na+ concentration sensing (131 ± 5 μA per log10Na+).
- Performance is comparable to state-of-the-art graphene chemical sensors.
Conclusions:
- The Lab-on-PCB platform offers an easy, low-cost, and scalable method for producing chemical sensor test strips.
- The demonstrated sensing capabilities highlight the platform's versatility for various analytes.
- This approach paves the way for widespread adoption of graphene-based chemical sensors.
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