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Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

53
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

66
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
66
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

51
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
51
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

32
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
32
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

53
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
53
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

31
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
31

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Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
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Omics and Artificial Intelligence in Kidney Diseases.

Nadja Grobe1, Josef Scheiber2, Hanjie Zhang1

  • 1Renal Research Institute, New York, NY.

Advances in Kidney Disease and Health
|February 1, 2023
PubMed
Summary
This summary is machine-generated.

Omics technologies offer future potential for kidney disease patient care through biomarker discovery and personalized medicine. Integration with artificial intelligence is needed for clinical diagnostics and treatment strategies in nephrology.

Keywords:
Artificial IntelligenceComputationalMachine learningModelingPredictionStratification

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Area of Science:

  • Nephrology
  • Genomics
  • Proteomics
  • Metabolomics
  • Systems Biology

Background:

  • Omics applications show promise for advancing kidney disease patient care.
  • Biomarker identification through omics levels can benefit patients in the short term.
  • Holistic integration of omics data is crucial for long-term individualized patient care.

Purpose of the Study:

  • To review the current and future relevance of omics applications in nephrology.
  • To highlight the potential of omics for understanding, risk stratification, and individualized treatment of kidney disease.
  • To identify the gap in combining omics with artificial intelligence for clinical nephrology.

Main Methods:

  • Literature review of omics applications in nephrology research.
  • Analysis of current evidence supporting omics in kidney disease.
  • Identification of future research directions for omics integration.

Main Results:

  • Omics data provide robust evidence for improved understanding and risk stratification in kidney disease.
  • Short-term benefits include specific biomarker analyses.
  • Long-term benefits require holistic integration for personalized care.

Conclusions:

  • Omics technologies hold significant future potential for improving clinical care in nephrology.
  • Further research is needed to integrate omics with artificial intelligence for clinical diagnostics and patient management.
  • Personalized medicine approaches in nephrology can be enhanced through advanced omics strategies.