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A Rare Case of Prurigo Pigmentosa in a Danish Sibling Couple
Maria Danielsen1, Kristine Pallesen1, Rikke Riber-Hansen2
1Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Abstract:
Prurigo pigmentosa (PP) is probably underdiagnosed due to lack of awareness. Previously, it was assumed that PP primarily affected Japanese females; however, more cases are reported worldwide, and the pathogenesis is still not completely understood. In this case report, we present two healthy Danish siblings, who developed PP approximately 2 weeks after starting a ketogenic diet, suggesting that both increased levels of ketone bodies in the blood together with a genetic predisposition might play a role in the development of PP.
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