[Control and correction of tissue respiration in an injured extremity with posttraumatic changes in blood...

An examination of ABB constants of the capillary blood in dynamics in 45 patients with posttraumatic alterations of the blood circulation has shown a correlation between them and the degree of disturbances of tissue respiration. Results of experiments in animals point to an improvement of tissue respiration as a response to the administration of methylene blue to the ischemic extremity. The methylene blue along with other drugs improving the microcirculation and tissue respiration was used in 4 patients and resulted in its normalization and prevented ischemic contracture.