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Related Experiment Video

Updated: Aug 12, 2025

Development of an In Vitro Ocular Platform to Test Contact Lenses
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Defining Daily Disposable Contact Lens Wear in a Clinical Study.

Heidi Wagner, Aaron B Zimmerman1, Dawn Lam2

  • 1College of Optometry, The Ohio State University, Columbus, Ohio.

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|February 2, 2023
PubMed
Summary

Many daily disposable contact lens wearers reuse lenses, potentially skewing safety data. Not using a lens case is a better indicator of true single-use contact lens wear.

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Area of Science:

  • Ophthalmology
  • Medical Device Regulation
  • Public Health

Background:

  • The U.S. Food and Drug Administration classifies contact lenses as medical devices, with daily disposables intended for single use.
  • Accurate classification of contact lens wear regimens is crucial for reliable safety comparisons between daily disposable and reusable lenses.
  • Misclassification of replacement regimens can lead to inaccurate risk assessments in contact lens studies.

Purpose of the Study:

  • To investigate and define reliable criteria for identifying daily disposable contact lens wearers within a clinical research setting.
  • To explore discrepancies in self-reported wear patterns versus actual lens usage.

Main Methods:

  • Secondary analysis of data from the Contact Lens Risk Survey (n=1059).
  • Descriptive statistics were used to analyze self-reported lens replacement, lens case usage, and manufacturer's recommended replacement frequency.
  • Daily disposable wearers were defined by self-reported daily replacement and non-use of a lens case; discrepancies were resolved by majority response.

Main Results:

  • 14.5% of participants were classified as daily disposable wearers.
  • Only 68.8% of identified daily disposable wearers showed agreement across all three classification factors (daily replacement, lens identification, no lens case use).
  • A significant portion (20.8%) of daily disposable wearers reported using a lens case, indicating potential reuse.

Conclusions:

  • The absence of lens case use appears to be a more accurate indicator of true single-use contact lens wear.
  • Approximately one in five daily disposable contact lens wearers may be storing and reusing their lenses.
  • This highlights a potential underestimation of risks associated with improper daily disposable contact lens wear in existing research.