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Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

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Monkeypox-Associated Disciform Keratitis.

Waleed K Alsarhani¹, Clara C Chan^1,2, Shelley R Boyd^1,2,3

¹Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.

|February 2, 2023

Summary

This summary is machine-generated.

Monkeypox (MPX) can cause disciform keratitis, a serious eye condition. Early treatment with antivirals and steroids helped resolve the patient's MPX-related eye inflammation and scarring.

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Area of Science:

Ophthalmology
Infectious Diseases
Virology

Background:

Monkeypox (MPX) is a viral disease that can cause systemic illness.
Ocular manifestations of MPX are uncommon but can be severe.
Disciform keratitis is a form of corneal inflammation.

Observation:

A case report details a 36-year-old male with MPX-associated disseminated pustular lesions and constitutional symptoms.
Ophthalmologic examination revealed disciform corneal edema and keratic precipitates in the affected eye.
MPX virus was confirmed by PCR in blood, skin lesions, and conjunctival swab.

Findings:

The patient received oral tecovirimat and topical prednisolone acetate for MPX-related keratitis.
Corneal findings resolved with treatment, leaving a small subepithelial scar.
This case highlights MPX as a potential cause of disciform keratitis.

Implications:

MPX-induced disciform keratitis can mimic other viral ocular infections.
Further clinical trials are necessary to establish optimal treatment protocols for MPX eye disease.
Prompt management is crucial to prevent vision loss from MPX-related ocular complications.