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Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
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Trace element zinc and skin disorders.

Pan Zou1, Yuxin Du1, Chunguang Yang2

  • 1Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Frontiers in Medicine
|February 3, 2023
PubMed
Summary
This summary is machine-generated.

Zinc is vital for skin health, acting as an antioxidant and supporting tissue integrity. Supplementation shows promise for numerous skin conditions, from infections to inflammatory and pigmentary diseases.

Keywords:
infectionsinflammationskintreatmentzinc

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Area of Science:

  • Dermatology
  • Nutritional Science
  • Biochemistry

Background:

  • Zinc is an essential trace element crucial for biological functions, including antioxidant activity and maintaining skin and mucous membrane integrity.
  • The skin is a significant reservoir for zinc, and its deficiency is linked to various dermatological disorders.
  • While genetic zinc deficiency (acrodermatitis enteropathica) is known, deficiency also occurs in other conditions.

Purpose of the Study:

  • To review existing literature on the application of zinc in dermatology.
  • To provide a comprehensive reference for the therapeutic use of zinc in various skin conditions.
  • To highlight the broad spectrum of dermatological applications for zinc supplementation.

Main Methods:

  • Literature review of studies on zinc in dermatology.
  • Analysis of research investigating zinc's role in skin health and disease.
  • Compilation of evidence for zinc supplementation in treating diverse dermatological conditions.

Main Results:

  • Zinc supplementation has demonstrated efficacy in treating a wide array of skin conditions.
  • These conditions include infectious diseases (e.g., viral warts, herpes), inflammatory disorders (e.g., acne, psoriasis, rosacea), pigmentary issues (e.g., vitiligo), and hair loss.
  • The review covers applications in tumor-associated, endocrine, and metabolic skin diseases as well.

Conclusions:

  • Zinc plays a critical role in dermatological health and disease management.
  • Zinc supplementation is a versatile therapeutic option for numerous skin conditions.
  • Further research and application of zinc in dermatology are warranted based on current evidence.