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A core outcome set for future research in ectopic pregnancy: an international consensus development study
Krystle Y Chong1, Sarah Solangon2, Kurt Barnhart3
1Department of Obstetrics and Gynecology, Monash University, Clayton, Australia; Monash Women's, Monash Health, Clayton, Australia.
Objective:
To address methodological deficiencies in published randomized controlled trials and systematic reviews, this study has developed a core outcome set to guide future research in ectopic pregnancy (EP).
Design:
To identify potential outcomes, we performed a comprehensive literature review and interviews with individuals with lived experience in EP. Potential core outcomes were then entered into a 3-round Delphi survey. A total of 154 participants from 6 continents, comprising health care professionals, researchers, and individuals with lived experience in EP, completed all 3 rounds of the Delphi survey. Outcomes were prioritized at 3 consensus development meetings, and recommendations were developed on how to report these outcomes where possible.
Setting:
Not applicable.
Patient(S):
Health care professionals, researchers, and individuals with lived experience in EP.
Intervention(S):
Not applicable.
Main Outcome Measure(S):
Consensus for inclusion in core outcome set.
Result(S):
Six outcomes reached full consensus, including treatment success, resolution time, the number of additional interventions, adverse events, mortality and severe morbidity, and treatment satisfaction.
Conclusion(S):
The core outcome set with 6 outcomes for EP will help standardize reporting of clinical trials, facilitate implementation of findings into clinical practice, and enhance patient-centered care.
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