[Current status of ophthalmic case registration study in the setting of real world study]

A new research concept has emerged in recent years, called real world study (RWS), which mainly relies on registration study and data management, and aims to evaluate the real effects and risks of actual clinical practice or health examination. This article compares the differences between RWS and randomized controlled trials, and summarizes the current situation of registration study in the medical field of RWS domestic and abroad, especially the current progress in the ophthalmic field. It is expected more medical centers will be able to conduct follow-ups based on the case registration system and carry out multicenter, large-scale RWS in the future.