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682
Kimura's Disease: A Confounding Condition
Shilpa Parikh1, Sheetal Sharma1,2, Jigna S Shah1
1Oral medicine and radiology department, Government Dental College, Ahmedabad, India.
Summary
Kimura disease (KD) is a rare inflammatory disorder affecting the head and neck. This case report details a young male diagnosed with KD, successfully treated with steroids and antihistamines.
Area of Science:
- Immunology
- Pathology
Background:
- Kimura disease (KD) is a chronic inflammatory lymphoproliferative disorder with unknown etiology.
- It typically affects the head and neck, presenting as soft-tissue masses involving salivary glands and lymph nodes.
- Characteristic features include peripheral blood eosinophilia and elevated serum IgE levels.
Purpose of the Study:
- To report a case of Kimura disease in a young Indian male.
- To highlight the diagnostic approach and treatment of this rare condition.
Main Methods:
- Case presentation of a 22-year-old male with parotid gland enlargement and lymphadenopathy.
- Diagnosis confirmed through histopathology and microscopic examination revealing lymphoid proliferation with eosinophilic infiltration.
Main Results:
- The patient presented with an asymptomatic parotid gland enlargement and lymphadenopathy.
- Histopathological findings confirmed Kimura disease.
- Treatment with steroids and antihistamines resulted in no recurrence during follow-up.
Conclusions:
- Kimura disease requires a combination of clinical, laboratory, and histopathological findings for definitive diagnosis.
- Steroid and antihistamine therapy can be effective in managing Kimura disease.
- Early diagnosis and treatment are crucial for favorable outcomes in Kimura disease.
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