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Kimura's Disease: A Confounding Condition.

Shilpa Parikh1, Sheetal Sharma1,2, Jigna S Shah1

  • 1Oral medicine and radiology department, Government Dental College, Ahmedabad, India.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
|February 6, 2023
PubMed
Summary
This summary is machine-generated.

Kimura disease (KD) is a rare inflammatory disorder affecting the head and neck. This case report details a young male diagnosed with KD, successfully treated with steroids and antihistamines.

Keywords:
Chronic eosinophilic inflammationKimura's diseaseParotid gland inflammatory diseases

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Area of Science:

  • Immunology
  • Pathology

Background:

  • Kimura disease (KD) is a chronic inflammatory lymphoproliferative disorder with unknown etiology.
  • It typically affects the head and neck, presenting as soft-tissue masses involving salivary glands and lymph nodes.
  • Characteristic features include peripheral blood eosinophilia and elevated serum IgE levels.

Purpose of the Study:

  • To report a case of Kimura disease in a young Indian male.
  • To highlight the diagnostic approach and treatment of this rare condition.

Main Methods:

  • Case presentation of a 22-year-old male with parotid gland enlargement and lymphadenopathy.
  • Diagnosis confirmed through histopathology and microscopic examination revealing lymphoid proliferation with eosinophilic infiltration.

Main Results:

  • The patient presented with an asymptomatic parotid gland enlargement and lymphadenopathy.
  • Histopathological findings confirmed Kimura disease.
  • Treatment with steroids and antihistamines resulted in no recurrence during follow-up.

Conclusions:

  • Kimura disease requires a combination of clinical, laboratory, and histopathological findings for definitive diagnosis.
  • Steroid and antihistamine therapy can be effective in managing Kimura disease.
  • Early diagnosis and treatment are crucial for favorable outcomes in Kimura disease.