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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
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The Ocular Trauma Score Underestimates Visual Recovery for the Most Severe Open-Globe Injuries.
Eli A Perez1, David A Ramirez1, Jared D Peterson1
1Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
Ophthalmology. Retina
|February 6, 2023
Summary
Open-globe injuries (OGI) in OTS category 1 showed better visual outcomes than predicted. Secondary pars plana vitrectomy (PPV) improved vision, suggesting expert evaluation for severe OGI cases.
Area of Science:
- Ophthalmology
- Trauma Surgery
Background:
- Open-globe injury (OGI) is a severe ocular trauma.
- The Ocular Trauma Score (OTS) is used to predict visual outcomes.
- Pars plana vitrectomy (PPV) is a surgical intervention for OGI.
Purpose of the Study:
- Compare actual visual outcomes in OGI patients with predictions from the Ocular Trauma Score (OTS).
- Evaluate the impact of pars plana vitrectomy (PPV) on visual outcomes after OGI.
Main Methods:
- Retrospective cohort study of 133 OGI patients treated between 2017-2020.
- Compared best-corrected visual acuity (VA) at follow-up with OTS predictions.
- Analyzed outcomes based on timing of PPV: primary, secondary, or no PPV.
Main Results:
- Eyes in OTS category 1 had better visual acuity than predicted (46% LP-HM vs. 15% predicted).
- Predictors of worse VA included older age and worse presenting VA.
- Secondary PPV did not significantly differ in final VA from primary PPV or no PPV groups, despite worse initial presentation.
Conclusions:
- The Ocular Trauma Score (OTS) may underestimate visual outcomes for the most severe OGI (category 1).
- Secondary PPV can lead to significant visual improvement in severe OGI cases.
- Consultation with a vitreoretinal surgeon is recommended for all severe OGI patients, particularly those in OTS category 1.
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