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Effect of levodopa treatment on contrast sensitivity in Parkinson's disease
C Bulens1, J D Meerwaldt, G J Van der Wildt
1Department of Neurology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands.
Annals of Neurology
|September 1, 1987
Abstract:
We studied contrast sensitivity function in 10 parkinsonian patients before and after levodopa treatment. Pretreatment contrast sensitivity function was abnormal in 16 of the 20 eyes. After treatment, only high-frequency loss was observed in 6 eyes. All other types of deficit disappeared under treatment. These changes of contrast sensitivity function following treatment suggest that dopamine is a functional transmitter in the visual pathways.