Related Experiment Video
Updated: Aug 11, 2025

Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction
Published on: October 13, 2017
Corneal Perforation Associated with Lacrimal Canaliculitis: A Case Series
Teruumi Minezaki1, Takaaki Hattori1, Motoko Shibata1
1Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
Purpose:
To report seven eyes of six patients diagnosed with corneal perforation and lacrimal canaliculitis in a single facility.
Methods:
Clinical records of patients with corneal perforation accompanied by lacrimal canaliculitis seen by the authors were reviewed.
Results:
Six patients (7 eyes) with corneal perforation accompanied by lacrimal canaliculitis were identified. All patients were female, and all were treated with topical antibiotics while five were receiving topical corticosteroids. Two patients had a history of dacryocystitis and three had systemic immune diseases. The corneal lesions did not respond to topical antibiotics but were effectively treated by removal of concretions in the lacrimal canaliculi and lacrimal duct drainage together with conjunctival autograft or corneal transplantation.
Conclusion:
Lacrimal canaliculitis is a risk factor for corneal perforation. When corneal perforation does not respond to antibiotics, lacrimal canaliculitis should be considered.

