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Related Experiment Video

Updated: Aug 11, 2025

Iris Fixation via External Pentagram Suturing
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UGH Syndrome Resolution after IOL Explantation and Concomitant Carlevale IOL Implantation.

Stylianos A Kandarakis1, Petros Petrou1, Andreas Katsimpris1

  • 1First Ophthalmology Department, "G.gennimatas" Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Ocular Immunology and Inflammation
|February 7, 2023
PubMed
Summary
This summary is machine-generated.

Carlevale intraocular lens (IOL) implantation after explantation effectively resolves UGH syndrome. This procedure improves visual acuity and reduces glaucoma medication needs, offering a viable surgical solution.

Keywords:
Glaucomahyphemascleral fixated IOLuveitic glaucomauveitis

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Area of Science:

  • Ophthalmology
  • Surgical Innovation

Background:

  • Uveitis-Glaucoma-Hyphema (UGH) syndrome presents complex management challenges.
  • Intraocular lens (IOL) explantation is often necessary in UGH syndrome cases.

Purpose of the Study:

  • To evaluate the efficacy of Carlevale IOL implantation in patients with UGH syndrome.
  • To assess surgical outcomes following IOL explantation and Carlevale IOL placement.

Main Methods:

  • Retrospective analysis of 28 patients with UGH syndrome.
  • Inclusion of patients undergoing IOL explantation and Carlevale IOL implantation.
  • Data collection on visual acuity (VA), intraocular pressure (IOP), glaucoma medications, and surgical interventions up to 6 months post-procedure.

Main Results:

  • Statistically significant improvement in mean visual acuity observed.
  • Complete resolution of uveitis in all treated patients.
  • Significant reduction in mean IOP and glaucoma medication requirements; 14% required further glaucoma surgery.

Conclusions:

  • Carlevale IOL implantation following explantation is a promising treatment for UGH syndrome.
  • The procedure enhances visual acuity and decreases reliance on glaucoma medications.
  • This surgical approach offers a viable solution for managing UGH syndrome complications.