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Updated: Aug 11, 2025

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
Published on: June 30, 2021
Vitamin A: a key coordinator of host-microbe interactions in the intestine
1Department of Biomedical Science, College of Medicine, Seoul National University, Seoul 03080; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul 03080; Institute of Infectious Diseases, Seoul National University College of Medicine, Seoul 03080, Korea.
Abstract:
The human intestine is home to a dense community of microbiota that plays a key role in human health and disease. Nutrients are essential regulators of both host and microbial physiology and function as key coordinators of host-microbe interactions. Therefore, understanding the specific roles and underlying mechanisms of each nutrient in regulating the host-microbe interactions will be essential in developing new strategies for improving human health through microbiota and nutrient intervention. This review will give a basic overview of the role of vitamin A, an essential micronutrient, on human health, and highlight recent findings on the mechanisms by which it regulates the host-microbe interactions. [BMB Reports 2023; 56(3): 133-139].
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