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Updated: Aug 11, 2025

Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes
Published on: March 9, 2019
Reprogrammable allosteric metamaterials from disordered networks
Nidhi Pashine1, Amir Mohammadi Nasab1, Rebecca Kramer-Bottiglio1
1School of Engineering & Applied Science, Yale University, New Haven, CT, 06520, USA. rebecca.kramer@yale.edu.
Abstract:
Prior works on disordered mechanical metamaterial networks-consisting of fixed nodes connected by discrete bonds-have shown that auxetic and allosteric responses can be achieved by pruning a specific set of the bonds from an originally random network. However, bond pruning is irreversible and yields a single bulk response. Using material stiffness as a tunable design parameter, we create metamaterial networks where allosteric responses are achieved without bond removal. Such systems are experimentally realized through variable stiffness bonds that can strengthen and weaken on-demand. In a disordered mechanical network with variable stiffness bonds, different subsets of bonds can be strategically softened to achieve different bulk responses, enabling a multiplicity of reprogrammable input/output allosteric responses.
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