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Exploring Intra-arterial Contrast Administration for Intraoperative Imaging Using a Swine Model
Rebecca N Treffalls1, Kelly Poe2, Hossam Abdou1
1R. Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD, USA.
Angiology
|February 8, 2023
Summary
Intra-arterial (IA) contrast offers better CT imaging than intravenous (IV) contrast for abdominal organs. IA contrast provides superior contrast-to-noise ratio with less volume and time.
Area of Science:
- Radiology
- Medical Imaging
- Endovascular Techniques
Background:
- Intraoperative computed tomography (CT) requires effective contrast administration.
- Intra-arterial (IA) contrast may offer advantages over intravenous (IV) contrast in terms of attenuation and volume.
Purpose of the Study:
- To compare the efficacy of IA versus IV contrast administration for organ-specific CT abdominal imaging.
Main Methods:
- Five anesthetized swine underwent IA and IV contrast administration protocols.
- Contrast attenuation (HU) and time to peak enhancement were measured in anatomical regions.
- Contrast-to-noise ratio (CNR) was evaluated for both methods.
Main Results:
- Both IA and IV contrast achieved adequate aortic opacification.
- IA contrast reached peak aortic attenuation significantly faster than IV contrast (8 vs 23 sec).
- IA administration resulted in a superior CNR compared to IV contrast (P < .001).
Conclusions:
- IA contrast provides adequate opacification with reduced bolus broadening and superior CNR.
- IA contrast is a viable alternative to IV contrast for organ-specific CT abdominal imaging, using less volume.
