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Updated: Aug 11, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Correlative imaging and histopathology of a complicated sinonasal teratocarcinosarcoma
Tineke van Zyl1, Leon Janse van Rensburg1,2, Komeela Naidoo3
1Department of Maxillofacial Radiology, Faculty of Dentistry, University of the Western Cape, Cape Town, South Africa.
Abstract:
Sinonasal teratocarcinosarcoma (SNTCS) is a highly malignant and rare tumour characterised by a complex admixture of teratomatous and carcinosarcomatous components. In the head and neck area, it almost exclusively occurs in the sinonasal cavities; however, rare instances of nasopharyngeal and oral cavity involvement have been reported, with fewer than 100 cases reported in the literature.
Contribution:
The contributed case involves the correlative CT, MRI and histopathology of a sinonasal teratocarcinosarcoma with intracranial involvement.

