[Analysis of cardiovascular risk factors in the stroke code. An approach in advanced ages.]
Alba García-Moreira1, Pablo Varela-Loimil1, Carmen Rodríguez-Jiménez2
1Complexo Hospitalario Universitario de Ourense, Servicio de Urgencias. Ourense. España.
Insights
High blood glucose, anticoagulant use, INR, and atrial fibrillation are key factors in preventing stroke and reducing mortality. Further research is needed to confirm the impact of sex and lifestyle on stroke outcomes.
Area of Science:
- Neurology
- Cardiology
- Public Health
Background:
- Cardiovascular risk factors (CVRF) significantly influence stroke incidence and outcomes.
- Understanding these factors is crucial for developing effective secondary prevention strategies.
- This study investigates CVRF in stroke patients in Ourense, Spain.
Purpose of the Study:
- To analyze the effect of CVRF on stroke patients.
- To identify key factors for secondary prevention of cerebrovascular events.
- To inform public health initiatives for chronic pathology management.
Main Methods:
- A longitudinal, retrospective, observational study of 153 stroke patients (mean age 76±12 years).
- Independent variables included international normalized ratio (INR), blood pressure, glycemia, atrial fibrillation (AF), anticoagulant use (ACO), smoking, and lipid levels.
- Dependent variables were stroke type, affected artery, and mortality at 30 days, 6 months, and 1 year.
Main Results:
- INR, glycemia, AF, and ACO were significantly associated with stroke type, affected artery, and/or mortality.
- High glycemia correlated with stroke type, affected artery, and mortality across all periods.
- Age was linked to mortality, and sex showed potential differential impacts on short-term and long-term mortality.
Conclusions:
- Prevention of cerebrovascular events and secondary mortality should prioritize managing high blood glucose, anticoagulant therapy, INR, and AF.
- Further large-scale studies are required to clarify the role of sex, smoking, diet, and other lifestyle factors in stroke mortality.
Objective:
The purpose of this study was to analyze the effect of cardiovascular risk factors (CVRF) in 153 patients who had suffered a stroke in the province of Ourense and where the stroke code had been activated.Its realization is part of the purpose of the authors to influence chronic pathology to prevent this specific event.
Methods:
A longitudinal, retrospective and observational study was applied to 153 patients with a mean age of 76±12 years who had presented some type of stroke. The independent variables were classified as quantitative (international normalized ratio [INR], blood pressure and glycemia) and in qualitative (atrial fibrillation [AF], consumption of anticoagulants [ACO], smoking and blood lipid levels). The dependent variables were the type of stroke, the affected artery, and patient mortality after thirty days, six months, and one year. For the qualitative variables, the non-parametric verification method of Kruskal-Wallis (K-W) and Mann-Whitney (M-W) was used for comparison of means and for Chi-square association.
Results:
INR was associated with the type of event and mortality at six and twelve months (p<0,001). Glycemia was related in a statistically significant way both with the type of event, the affected artery and with mortality in the three periods. Both AF and OACs were associated with the type of event and the artery affected, the latter also with one-year mortality. Age was related to mortality in the three periods without becoming significant at thirty days. Being a man could be a risk factor for thirty -day mortality (OR>1) and being a woman for one-year mortality. Regarding the type of intervention performed, undergoing fibrinolysis or thrombectomy increased the risk of mortality compared to combined treatment, the relationship between thrombectomy and increased mortality being statistically significant exclusively in the six-month period.
Conclusions:
According to the results obtained, the prevention of cerebrovascular events and secondary mortality should focus mainly on high blood glucose levels, the consumption of anticoagulants, INR, and the presence of AF as cardiovascular risk factors. Studies with a larger sample size are needed to establish if there really is an impact on mortality based on sex, as well as to determine with greater certainty if habits such as smoking, poor diet and other factors play a relevant role.
Related Concept Videos
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Coronary Artery Disease I: Introduction
Atherosclerosis IV: Nursing Management
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Coronary Artery Disease IV: Preventive Measures
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...


