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05:16
Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
Published on: August 4, 2021
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Pregnancy outcomes following recurrent miscarriage.
Niamh Fee1, Aoife McEvoy2, Sarah Cullen2
1National Maternity Hospital, Dublin, Ireland. drniamhfee@gmail.com.
Irish Journal of Medical Science
|February 9, 2023
Summary
Women attending a recurrent miscarriage clinic have a high subsequent live birth rate. Specialized care for recurrent pregnancy loss does not increase the risk of adverse outcomes.
Area of Science:
- Reproductive Medicine
- Obstetrics
- Genetics
Background:
- Recurrent miscarriage affects 1-2% of the population.
- Existing literature primarily focuses on causes, treatment, and live birth rates.
Purpose of the Study:
- To evaluate reproductive outcomes in patients treated at a specialist recurrent miscarriage clinic.
- To assess the efficacy of dedicated recurrent miscarriage services.
Main Methods:
- Prospective analysis of patients attending a recurrent miscarriage clinic.
- Data collected from January 2014 to January 2021.
- Inclusion of 299 patients who had a subsequent pregnancy.
Main Results:
- A 75.3% subsequent live birth rate was observed.
- Adverse outcomes included preeclampsia (2.2%), pregnancy-induced hypertension (2.2%), fetal growth restriction (5.3%), and preterm birth (1.8% ≤34 weeks, 6.6% >34 weeks).
- The majority of patients (55.6%) had a previous live birth, with a median age of 37 years.
Conclusions:
- Specialist recurrent miscarriage clinics achieve high live birth rates for subsequent pregnancies.
- Pregnancy after recurrent loss is not associated with elevated risks of adverse outcomes.
- Dedicated clinical services offer effective management for recurrent pregnancy loss.
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