Mpox-A Rapidly Evolving Disease.

Area of Science:

• Dermatology
• Infectious Diseases
• Public Health

Background:

• The 2022 mpox outbreak emerged globally during the ongoing COVID-19 pandemic.
• Mpox clinical presentation often includes skin findings, potentially misdiagnosed as sexually transmitted infections.
• Accurate identification of mpox dermatological manifestations is critical for patient care.

Purpose of the Study:

• To provide an overview of the evolution of mpox skin findings.
• To trace the historical changes in mpox presentation since its initial human description.
• To aid clinicians in differentiating mpox from other skin conditions.

Main Methods:

• Review of historical and contemporary clinical descriptions of mpox.
• Analysis of dermatological manifestations reported in the 1970s and the 2022 outbreak.
• Synthesis of information on the changing clinical presentation of mpox.

Main Results:

• Mpox skin findings have evolved since its initial recognition in humans in 1970.
• The current outbreak's presentation may differ from historical cases, posing diagnostic challenges.
• Dermatological manifestations are a key feature distinguishing mpox from COVID-19.

Conclusions:

• Understanding the evolution of mpox skin lesions is essential for timely diagnosis.
• Clinical vigilance is required to differentiate mpox from other dermatological conditions.
• This overview aids in recognizing the diverse presentations of mpox.