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Published on: November 10, 2016
A new ratiometric molecularly imprinted electrochemical sensor for the detection of Sunset Yellow based on gold
1School of Food Science and Engineering, Key Laboratory of Tropical and Vegetables Quality and Safety for State Market Regulation, Hainan University, Haikou 570228, China; Key Laboratory of Fermentation Engineering (Ministry of Education), College of Bioengineering and Food, Hubei University of Technology, Wuhan 430068, China.
Abstract:
Since a high dosage or excessive intake of Sunset Yellow (SY) may pose a threat to human health, it is in great demand to construct an effective method to detect and control SY. Based on the molecularly imprinted polymers (MIPs) and dual-signal output mode, a ratiometric molecularly imprinted electrochemical sensor (RMIECs) was developed for sensitive detection of SY. AuNPs not only provided a large specific surface area to enhance the electron transfer rate but also served as a reference signal (S1), together with SY signal (S2), to produce dual signals. For a proof-of-application study, RMIECs was applied to detect SY with a wide linear range from 10 nM to 100 μM and a low detection limit (LOD) of 1.60 nM (S/N = 3, n = 3). Besides, the method was applied in spiked food samples with recoveries of 94.0 ∼ 97.0 % as well as relative errors of 5.4 ∼ 8.3 %, revealing its promising potential in detection of SY.
