[Effect of keratinized gingival width on periodontal regenerative surgery for the treatment of intrabony defects: a retrospective study]
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Updated: Aug 11, 2025

A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
Published on: January 12, 2019
Hao-Hao Liu1, Yi Hu, Chen Zhang
1Department of Periodontology, Shanghai Stomatological Hospital and School of Stomatology, Fudan University; Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases. Shanghai 200001, China.
Purpose:
To evaluate the effect of keratinized tissue width (KTW) on periodontal regenerative surgery for the treatment of intrabony defects.
Methods:
The clinical data of 14 patients (44 intrabony defect sites) treated with periodontal regenerative surgery were retrospectively analyzed at baseline and 2-year of follow-up. Forty four sites were divided into KTW2 mm group and KTW≤2 mm group according to KTW at baseline. Periodontal clinical indicators of the 2 groups were analyzed by SPSS 25.0 software package.
Results:
At 2-year post-treatment, probing depth (PD) and clinical attachment loss (CAL) in the 2 groups were decreased significantly compared with those at baseline(P<0.05). There was no significant difference in ΔPD, but ΔCAL in KTW2 mm group was significantly greater than that in KTW≤2 mm group.
Conclusions:
Periodontal regenerative surgery for the treatment of intrabony defects can effectively reduce periodontal pocket inflammation, decrease periodontal pocket depth and increase the level of attachment. When the width of the keratinized gingiva is insufficient(KTW≤2 mm), the regeneration of the attachment level obtained by surgery is limited, and the efficacy of regenerative surgery is poor.
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