Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Stroke Volume01:27

Regulation of Stroke Volume

3.4K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
3.4K
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

1.4K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.4K
Atherosclerosis IV: Nursing Management01:23

Atherosclerosis IV: Nursing Management

31
Nursing management for a patient with arteriosclerosis involves a comprehensive approach focusing on lifestyle modification, disease monitoring, education, and symptomatic care. Here is an overview of effective nursing strategies:Assessment and Monitoring: Initial and ongoing assessments are crucial. Nurses must document the patient's medical history, including any hypertension, diabetes, hyperlipidemia, and other cardiovascular diseases. Assessments also cover family history and lifestyle...
31
Cardiac Output II: Effect of Stroke Volume on Cardiac Output01:22

Cardiac Output II: Effect of Stroke Volume on Cardiac Output

1.2K
Cardiac output (CO), the amount of blood the heart pumps per minute, is a parameter in cardiovascular physiology determined by stroke volume and heart rate. Stroke volume, the amount of blood pushed from one of the ventricles per heartbeat, is influenced by preload, afterload, and contractility.
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
1.2K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

912
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
912

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thrombectomy for Pediatric Large Vessel Occlusion Stroke With Mild Presenting Symptoms.

Neurology·2026
Same author

Volumetric Analysis of Deep Cerebellar and Thalamic Nuclei in Spastic Cerebral Palsy.

Journal of computer assisted tomography·2026
Same author

Hospital Care for Pediatric Stroke in the United States: Resource Utilization, Charges, Comorbidities, Death, and Disability (2003-2022).

Pediatric neurology·2026
Same author

Navigating workforce challenges and strategies for sustainable mental health inpatient services-perspectives from Victoria's public mental health sector.

International journal of mental health systems·2026
Same author

Optimisation of Backing Layer Formulations via Rational Polymer Selection to Improve the Insertion of Dissolving Microneedles Into Skin.

Molecular pharmaceutics·2026
Same author

Correction: TOPSS: TOlerability of transcranial direct current stimulation in Pediatric Stroke Survivors.

Frontiers in human neuroscience·2025

Related Experiment Video

Updated: Aug 10, 2025

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
09:11

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability

Published on: February 23, 2016

22.0K

Stroke in the young.

Stuart Fraser1,2, Lisa Pabst3, Fiona Smith4

  • 1Division of Child and Adolescent Neurology, Department of Pediatrics, The University of Texas McGovern Medical School.

Current Opinion in Neurology
|February 10, 2023
PubMed
Summary
This summary is machine-generated.

Stroke incidence is rising in young adults, with poorer outcomes in developing nations. Advances in thrombectomy, genetic testing, and treatments like hydroxyurea offer new hope for pediatric and young adult stroke patients.

More Related Videos

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

14.9K
Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
05:32

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

2.1K

Related Experiment Videos

Last Updated: Aug 10, 2025

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
09:11

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability

Published on: February 23, 2016

22.0K
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

14.9K
Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
05:32

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

2.1K

Area of Science:

  • Neurology
  • Pediatrics
  • Public Health

Background:

  • Stroke in children and young adults presents a significant global health challenge, marked by increasing incidence in young adults and disparities in outcomes.
  • The disease imposes substantial societal costs and a high burden of long-term disability.

Approach:

  • This review synthesizes recent findings on stroke epidemiology, etiologies, and treatment modalities in pediatric and young adult populations.
  • It examines emerging therapeutic strategies and diagnostic advancements.

Key Points:

  • Rising stroke incidence in young adults necessitates updated management guidelines, including consideration of patent foramen ovale closure for cryptogenic stroke.
  • Thrombectomy is showing promise in carefully selected pediatric cases of acute ischemic stroke.
  • Sickle cell disease remains a major contributor to stroke burden; hydroxyurea offers cost-effective prevention in children.
  • Advances in genetic testing are improving outcomes for monogenic stroke causes like adenosine deaminase 2 deficiency, hemophilia, and Fabry's disease.

Conclusions:

  • Recent therapeutic and diagnostic advancements are improving care access for large vessel occlusion in children and rare stroke causes in adults.
  • Future research holds potential for novel treatments for monogenic stroke and expanded access to hyperacute therapies for young stroke patients.