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On the non-existence of a tryptic peptide with biological activity derived from mouse nerve growth factor

C J Springer1, C A Vernon

  • 1Department of Chemistry, University College, London, U.K.

Biochimica Et Biophysica Acta
|November 26, 1987
PubMed

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Enzyme-linked Receptors01:00

Enzyme-linked Receptors

Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...