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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Hormones and Bone Tissue01:17

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

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The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
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Related Experiment Video

Updated: Aug 10, 2025

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
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Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma

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Body composition changes following total thyroidectomy: A one-year follow-up study.

Suleyman Utku Celik1, Can Konca2

  • 1Department of General Surgery, Gulhane Training and Research Hospital, Ankara, Turkey; Department of General Surgery, Ankara University School of Medicine, Ankara, Turkey.

Endocrinologia, Diabetes Y Nutricion
|February 10, 2023
PubMed
Summary

Total thyroidectomy significantly alters body weight and fat mass. Higher baseline free-T3 and lower body fat predict greater fat mass gain after surgery.

Keywords:
Análisis de impedancia bioeléctricaBioelectrical impedance analysisBody compositionBody fatBody weightComposición corporalGrasa corporalPeso corporalTiroidectomía totalTotal thyroidectomy

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Area of Science:

  • Endocrinology
  • Metabolic Health
  • Surgical Outcomes

Background:

  • Thyroid hormones are crucial for regulating body weight.
  • Understanding post-thyroidectomy body composition changes is important for patient management.

Purpose of the Study:

  • To investigate the impact of total thyroidectomy on body weight and composition.
  • To identify factors influencing weight and fat mass changes after surgery.

Main Methods:

  • Retrospective cohort study of patients undergoing total thyroidectomy.
  • Collected demographic, surgical, and thyroid function data.
  • Assessed body composition using bioelectrical impedance analysis at baseline and 12 months post-surgery.

Main Results:

  • Significant increases in weight, BMI, and fat mass observed post-thyroidectomy.
  • 72.7% of patients experienced weight gain.
  • Higher baseline free-T3 and lower baseline percent body fat were associated with increased fat mass.

Conclusions:

  • Total thyroidectomy leads to significant changes in body weight and fat mass.
  • Baseline free-T3 levels and body fat percentage are key predictors of fat mass gain post-surgery.