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Published on: December 9, 2017
Fatty acid acylation of proteins in Physarum polycephalum
1National Institute for Medical Research, Mill Hill, London, U.K.
Abstract:
We have investigated the occurrence of protein-fatty acid acylation by metabolic incorporation of [3H]myristic and [3H]palmitic acids in Physarum polycephalum. We show that this organism contains fatty acylated proteins with mainly myristic acid covalently attached in alkali-stable linkages, probably amides. We find no evidence for ester-linked fatty acids, in contrast to the situation in vertebrate cells.
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