Related Experiment Videos
Gene-dependent effect of lithium on circadian rhythms in mice (Mus musculus)
1Department of Biology, Skidmore College Saratoga Spring, NY 12866.
Chronobiology International
|January 1, 1986
Abstract:
Lithium has been shown to lengthen free-running circadian periods in a variety of species. Here we show that lithium carbonate differentially lengthens the free-running period of a circadian wheel running rhythm in BALB/CByJ and C57BL/10Sn inbred mouse strains. This result supports previous evidence that lithium lengthens mammalian circadian rhythms, and also demonstrates that gene differences can mediate individual differences in response to lithium treatment.