Related Experiment Video
Updated: Aug 10, 2025

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
Published on: October 13, 2023
Knowledge Graph: Applications in Tracing the Source of Large-Scale Outbreak - Beijing Municipality, China, 2020-2021
Ying Shen1, Yonghong Liu1, Xiaokang Jiao2
1Beijing Office of Global Health, Beijing Center for Disease Prevention and Control, Beijing, China.
Introduction:
Tracing transmission paths and identifying infection sources have been effective in curbing the spread of coronavirus disease 2019 (COVID-19). However, when facing a large-scale outbreak, this is extremely time-consuming and labor-intensive, and resources for infection source tracing become limited. In this study, we aimed to use knowledge graph (KG) technology to automatically infer transmission paths and infection sources.
Methods:
We constructed a KG model to automatically extract epidemiological information and contact relationships from case reports. We then used an inference engine to identify transmission paths and infection sources. To test the model's performance, we used data from two COVID-19 outbreaks in Beijing.
Results:
The KG model performed well for both outbreaks. In the first outbreak, 20 infection relationships were identified manually, while 42 relationships were determined using the KG model. In the second outbreak, 32 relationships were identified manually and 31 relationships were determined using the KG model. All discrepancies and omissions were reasonable.
Discussion:
The KG model is a promising tool for predicting and controlling future COVID-19 epidemic waves and other infectious disease pandemics. By automatically inferring the source of infection, limited resources can be used efficiently to detect potential risks, allowing for rapid outbreak control.
More Related Videos
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
09:26Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
Published on: June 30, 2023
Related Concept Videos
Steps in Outbreak Investigation
Causality in Epidemiology
Principles of Disease Surveillance
Single Nucleotide Polymorphisms-SNPs
Applications of GIS: Disaster Management and Emergency Response
Statistical Methods for Analyzing Epidemiological Data