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Updated: Aug 10, 2025

Author Spotlight: Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms
Published on: March 15, 2024
Leveraging type 1 diabetes human genetic and genomic data in the T1D Knowledge Portal
Parul Kudtarkar1, Maria C Costanzo2,3, Ying Sun1
1Department of Pediatrics, University of California San Diego, La Jolla CA.
Abstract:
Translating genetic discoveries for type 1 diabetes (T1D) into mechanistic insight can reveal novel biology and therapeutic targets but remains a major challenge. We developed the T1D Knowledge Portal (T1DKP), a disease-specific resource of genetic and functional annotation data that enables users to develop hypotheses for T1D-based research and target discovery. The T1DKP can be used to query genes and genomic regions for genetic associations, identify epigenomic features, access results of bioinformatic analyses, and obtain expert-curated resources. The T1DKP is available at http://t1d.hugeamp.org .
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