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Related Concept Videos

Measurements of Strain01:27

Measurements of Strain

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Strain quantifies the deformation of a material under force, typically measured as normal strain, which represents the change in length when compared with the original length. Electrical strain gauges are used for enhanced accuracy. These devices consist of a conductive wire mounted on a paper backing that adheres to the material's surface. These gauges operate on the piezoresistive effect, where the wire's electrical resistance changes in response to mechanical deformation. The strain...
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Strain and Elastic Modulus01:15

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The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...
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Three-Dimensional Analysis of Strain01:29

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Three-dimensional strain analysis is crucial for understanding how materials deform under stress, particularly in elastic, homogeneous materials. This method employs principal stress axes to simplify complex stress states into more understandable forms. Subjected to stress, a small cubic element within a material either expands or contracts along these axes, transforming into a rectangular parallelepiped. This transformation effectively illustrates the material's deformation. The principal...
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Related Experiment Video

Updated: Aug 10, 2025

Measuring Local Tissue Strains in Tendons via Open-Source Digital Image Correlation
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Measuring Local Tissue Strains in Tendons via Open-Source Digital Image Correlation.

Stanton Godshall1, Krishna Pedaprolu1, Erica Vasti1

  • 1Department of Biomedical Engineering, Pennsylvania State University.

Journal of Visualized Experiments : Jove
|February 13, 2023
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Summary

Researchers developed an accessible tool to measure cell strains in tendons. This validated augmented-Lagrangian digital image correlation (ALDIC) algorithm accurately quantifies local tissue strains, aiding tendon remodeling research.

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Area of Science:

  • Biomechanics
  • Cellular Biology
  • Biomaterials Science

Background:

  • Understanding in situ tendon cell strains is crucial for tissue remodeling research.
  • Existing techniques for measuring local strains in tendon explants lack reported accuracy and public algorithms.
  • Difficulty in widespread measurement hinders progress in tendon biomechanics.

Purpose of the Study:

  • To create a validated, accessible, and user-friendly analysis tool for measuring local tissue strains in tendon explants.
  • To adapt and validate an augmented-Lagrangian digital image correlation (ALDIC) algorithm for 2D strain measurement in mouse Achilles tendons.
  • To incorporate a novel technique for assessing algorithm accuracy without external validation.

Main Methods:

  • Adapted a publicly available augmented-Lagrangian digital image correlation (ALDIC) algorithm to track cell nucleus displacements in mouse Achilles tendons under uniaxial tension.
  • Validated strain accuracy using digitally transformed images and comparison with photobleached line measurements.
  • Implemented a reference image reconstruction technique for accuracy assessment.

Main Results:

  • The ALDIC algorithm accurately measures strains up to 0.1 with an accuracy of 0.00015.
  • The reference image reconstruction method effectively identified erroneous data.
  • Approximately 85% of the displacement field was accurate in samples with good data.
  • Measured strains in mouse Achilles tendons align with existing literature.

Conclusions:

  • The developed ALDIC-based algorithm provides a highly accurate and adaptable tool for quantifying local tissue strains in tendons.
  • This validated, publicly available tool facilitates widespread measurement of tendon cell strains.
  • The findings contribute to a better understanding of tendon biomechanics and tissue remodeling.