Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Facially distributed pattern-evoked potentials in multiple sclerosis.

E Adachi-Usami1

  • 1Department of Ophthalmology, School of Medicine, Chiba University, Japan.

Documenta Ophthalmologica. Advances in Ophthalmology
|March 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes of macular and RNFL thicknesses measured by Stratus OCT in patients with early stage diabetes.

Eye (London, England)·2008
Same author

Use of blue-on-yellow perimetry for detection of sectoranopia.

Eye (London, England)·2004
Same author

Relative hypersensitivity in healthy eye by frequency doubling perimetry in patients with severely damaged contralateral eye.

The British journal of ophthalmology·2003
Same author

Optic disc metastasis presenting as an initial sign of recurrence of adenoid cystic carcinoma of the larynx.

Eye (London, England)·2003
Same author

Criteria for early detection of temporal hemianopia in asymptomatic pituitary tumor.

Eye (London, England)·2002
Same author

Fish oil (polyunsaturated fatty acid) prevents ischemic-induced injury in the mammalian retina.

Experimental eye research·2002
Same journal

The relationship between foveal anatomy and retinal function in oculocutaneous albinism.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Early onset primary angle closure and foveal retinoschisis associated with a pseudo-homozygous CRB1 pathogenic variant.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Bilateral perifoveal macular ischemia in non-proliferative Duchenne muscular dystrophy-associated retinopathy: a case report.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Association between dynamic pupil parameters and corneal sub-basal nerve plexus morphology.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Structure-function relationship between handheld photopic negative response and macular GCIPL thickness in chronic optic neuropathy.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Clinical course of a patient with PRSS56-associated nanophthalmos (isolated microphthalmia) and uveal effusion syndrome.

Documenta ophthalmologica. Advances in ophthalmology·2026
See all related articles

Pattern-evoked potentials (PERGs) can be detected in the facial area of multiple sclerosis patients with optic neuritis. However, reduced PERG amplitude was observed even in MS patients without optic neuritis.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Neurology

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease.
  • Optic neuritis is a common early symptom of MS.
  • Assessing visual pathway involvement in MS is crucial.

Purpose of the Study:

  • To investigate the utility of pattern-evoked potentials (PERGs) in multiple sclerosis patients.
  • To evaluate PERGs in patients with and without optic neuritis.
  • To explore the correlation between PERG findings and clinical status.

Main Methods:

  • Studied 56 established cases of multiple sclerosis.
  • Recorded pattern-evoked potentials (PERGs) using 16 electrodes on the scalp and facial area.
  • Analyzed PERG amplitude and peak latency in relation to optic neuritis and visual acuity.

Related Experiment Videos

Main Results:

  • PERGs were obtainable in the facial area of MS patients with optic neuritis, except in chronic cases.
  • A significant reduction in PERG amplitude was observed in MS patients, including those without optic neuritis.
  • No correlation was found between visual acuity and PERG amplitude or latency.

Conclusions:

  • Facial pattern-evoked potentials may offer insights into visual pathway dysfunction in multiple sclerosis.
  • PERG amplitude reduction is a potential biomarker for subclinical visual involvement in MS.
  • Further research is warranted to explore the diagnostic and prognostic value of PERGs in MS.