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Updated: Aug 10, 2025

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Simultaneous Brightfield, Fluorescence, and Optical Coherence Tomographic Imaging of Contracting Cardiac Trabeculae Ex Vivo
Published on: October 2, 2021
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Triple-clad W-type fiber mitigates multipath artifacts in multimodal optical coherence tomography
Optics Express
|February 14, 2023
Summary
Multimodal optical coherence tomography (OCT) using double-clad fiber suffers from artifacts. A novel W-type fiber enables artifact-free OCT and autofluorescence imaging in endoscopic systems.
Area of Science:
- Biomedical Optics
- Fiber Optics Engineering
- Medical Imaging
Background:
- Multimodal endoscopic imaging combines optical coherence tomography (OCT) with other modalities for enhanced diagnostics.
- Double-clad fiber (DCF) offers potential for multimodal endoscopic systems but introduces multipath artifacts in OCT.
- Existing single-mode fiber OCT systems lack the multimodal capabilities of DCF.
Purpose of the Study:
- To investigate the mechanisms of multipath artifacts in DCF-based OCT.
- To propose and evaluate a W-type fiber as a solution for artifact-free multimodal endoscopic OCT.
- To demonstrate the efficacy of W-type fiber in an endoscopic system for high-quality imaging.
Main Methods:
- Modal analysis of W-type fiber using commercial software and experimental measurements.
- Comparison of modal content between W-type fiber, DCF, and single-mode fiber.
- Implementation of a W-type fiber rotary catheter in a DCF-based endoscopic OCT and autofluorescence imaging (AFI) system.
Main Results:
- Multipath artifacts in DCF-OCT were identified and linked to modal contents.
- W-type fiber simulations showed superior modal control compared to DCF.
- The W-type fiber rotary catheter successfully enabled artifact-free OCT and AFI of a human fingertip.
Conclusions:
- W-type fiber is a viable solution for achieving high-quality, artifact-free OCT in multimodal endoscopic systems.
- This advancement facilitates improved diagnostic capabilities in minimally invasive procedures.
- The proposed W-type fiber design overcomes limitations of DCF for advanced endoscopic imaging.
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