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Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
The acute bronchiolitis rebound in children after COVID-19 restrictions: a retrospective, observational analysis
Antonietta Curatola1, Benedetta Graglia2, Serena Ferretti3
1. c.anto91@hotmail.it.
Insights
The post-COVID period saw an earlier, shorter bronchiolitis season with increased hospitalizations in children. Respiratory Syncytial Virus (RSV) was the most common cause, with SARS-CoV-2 rarely identified.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Bronchiolitis is a leading cause of pediatric illness and hospitalization.
- Understanding seasonal trends and etiology is crucial for public health management.
Purpose of the Study:
- To compare Pediatric Emergency Department (PED) admissions for bronchiolitis during the post-COVID period with previous seasons.
- To analyze the etiology of bronchiolitis during and after the COVID-19 pandemic.
Main Methods:
- A comparative analysis of demographic, clinical, and microbiological data.
- Data collected from children admitted to the PED with bronchiolitis between September 2021 and March 2022 (post-COVID period) compared to previous seasons (COVID and pre-COVID).
Main Results:
- The post-COVID bronchiolitis season began earlier with a peak in November 2021.
- Higher rates of high-priority codes (61.4%) and hospitalizations were observed in the post-COVID period compared to pre-COVID (34.8%).
- Respiratory Syncytial Virus (RSV) was prevalent (60.2%), followed by Human Rhinovirus (30.1%); SARS-CoV-2 was rarely detected (1.5%).
Conclusions:
- The post-COVID period exhibited an early, intense, and short bronchiolitis season with increased hospitalization rates.
- SARS-CoV-2 was an infrequent cause of bronchiolitis in young children during this period.
Background And Aim:
Bronchiolitis represents the main cause of illness and hospitalization in infants and young children. The aim of this study was to compare the Pediatric Emergency Department (PED) admissions for bronchiolitis during the post-COVID (Coronavirus disease) period to those of previous seasons and to analyze their etiology during COVID and post-COVID period.
Methods:
We compared demographics, clinical and microbiological data of children admitted to PED with bronchiolitis between September 2021 and March 2022 (post-COVID period) to the previous seasons (COVID and pre-COVID period).
Results:
During the post-COVID period the bronchiolitis season started earlier than usual, with a peak reached in November 2021; a gradual reduction was subsequently observed between December 2021 and January 2022. Our data showed a prevalence of High Priority code in children admitted to the PED with bronchiolitis during the post-COVID period (61.4%) compared the pre-COVID period (34.8%) (p=0.00). Also regarding the hospitalization of these patients, we found a major rate of hospitalization during this epidemic season (p=0.035). In addition, only 4 (1.5%) of the tested children resulted positive for SARS-CoV-2 and all of them were admitted to PED during the post-COVID period. The search for the other respiratory viruses showed during the current season a prevalence of respiratory syncytial virus (RSV) (60.2%), followed by Human Rhinovirus (30.1%).
Conclusions:
The post-COVID period was characterized by an early and short-term peak in acute bronchiolitis, with an increased rate of hospitalization. In addition, SARS-CoV-2 infection was rarely cause of bronchiolitis in children under 2 years old.
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